PH for blood

During exercise, the muscles use up oxygen as they convert chemical energy in glucose to mechanical energy. This O2 comes from hemoglobin in the blood. CO2 and H+ are produced during the breakdown of glucose, and are removed from the muscle via the blood.

The production and removal of CO2 and H+, together with the use and transport of O2, cause chemical changes in the blood. These chemical changes, unless offset by other physiological functions, cause the pH of the blood to drop. If the pH of the body gets too low (below 7.4), a condition known as acidosis results. This can be very serious, because many of the chemical reactions that occur in the body, especially those involving proteins, are pH-dependent.

Ideally, the pH of the blood should be maintained at 7.4. If the pH drops below 6.8 or rises above 7.8, death may occur. Fortunately, we have buffers in the blood to protect against large changes in pH.


Decrease in PH

The kidneys help remove excess chemicals from the blood, as discussed in the kidney dailysis tutorial. It is the kidneys that ultimately remove (from the body) H+ ions and other components of the pH buffers that build up in excess. Acidosis that results from failure of the kidneys to perform this excretory function is known as metabolic acidosis.

However, excretion by the kidneys is a relatively slow process, and may take too long to prevent acute acidosis resulting from a sudden decrease in pH (e.g., during exercise). The lungs provide a faster way to help control the pH of the blood. The increased-breathing response to exercise helps to counteract the pH-lowering effects of exercise by removing CO2, a component of the principal pH buffer in the blood. Acidosis that results from failure of the lungs to eliminate CO2 as fast as it is produced is known as respiratory acidosis

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الاس الهيدروجينى للدم

الاس الهيدروجيني للدم والنسبه الطبيعيه
7.4 ولو قلت النسبه معناته ان حموضة الدم تزيد مثل في حالات الفشل الكلوي